Free Download Neanderthal Man: In Search of Lost Genomes
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Neanderthal Man: In Search of Lost Genomes
Free Download Neanderthal Man: In Search of Lost Genomes
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Review
"Pääbo provides a riveting, personal account of the development of paleogenetics and the technical revolution that made the field possible."―Science"Neanderthal Man is a revealing history of a new scientific field."―Carl Zimmer, New York Times Book Review"If there is one name associated with ancient DNA, it is Svante Pääbo.... Neanderthal Man is perfectly timed, beautifully written and required reading."―Nature"Pääbo has provided us with a fabulous account of three decade of research into ancient DNA, culminating in 2010 with the publication of the Neanderthal genome."―New York Review of Books"Highly recommended." ―Choice"The world's foremost expert on recovering ancient DNA tells the inside story of what it took to reconstruct the Neanderthal genome."―The Christian Century, Essential Books on Evolution and Human Origins"This is a fascinating story of how modern science and especially computer technology is opening vistas onto our prehistoric history." ―The Explorers Journal"Pääbo provides a fascinating look at how his personal life intersected with the founding of a scientific field that has revolutionized evolution." ―Science News"Pääbo paints a picture of how a major scientific advance rose out of a mix of politics, persuasion, careful management, and struggles with technology and technique. For that alone, it's valuable."―Ars Technica"Scientific understanding of earlier humans is fast evolving. For the nonce, this is a go-to volume on the subject for serious readers." ―Library Journal
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About the Author
Svante Pääbo is the founder of the field of ancient DNA. The director of the department of genetics at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Pääbo has been featured in the New York Times, Newsweek, National Geographic, and The Economist, as well as on NPR, PBS, and BBC. In 2009 Time named him one of the 100 Most Influential People in the World. Pääbo lives in Leipzig, Germany.
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Product details
Paperback: 288 pages
Publisher: Basic Books; 1 edition (March 24, 2015)
Language: English
ISBN-10: 0465054951
ISBN-13: 978-0465054954
Product Dimensions:
5.8 x 1 x 8.5 inches
Shipping Weight: 9.6 ounces (View shipping rates and policies)
Average Customer Review:
4.4 out of 5 stars
231 customer reviews
Amazon Best Sellers Rank:
#90,676 in Books (See Top 100 in Books)
With the completion of the full human genome sequence in 2003 and the rapid fall in DNA sequencing costs over the subsequent 10 years, we have been awaiting major advancements in many fields such as Healthcare, Agriculture, Drug Discovery and so on. However, the progress has been slow and the deluge of genome sequence data has been a tough problem to handle.But, Svante Paabo in this fascinating book on the 'Neanderthal Man' shows how the new technologies have enabled him to sequence the genomes of our extinct relatives - the Neanderthals and the Denisovans. The data proves how our ancestors moved out of Africa about 50,000 years back and interbred to a small extent (2 to 7% of our genes come from them) with the Neanderthals and Denisovans and maybe drove them to extinction. Many interesting facts come out of these studies such as, (a) that gene flow seems to have been from the Neanderthals to us (and not the other way), (b) the founding population of the Neanderthals also seems to have pretty small like in the case of the humans (c) we split from the Neanderthals about 500,000 years back (d) the Denisovans split about 1 million years back (e) the Denisovans seem to be closer to the Neanderthals than to humans, and much more...The book is not only fun to read, but Paabo's detective mode of story telling will also keep the reader focused. By mixing his personal stories with scientific research, Paabo provides a refreshing frankness to the narrative. We get a direct view of the challenges in scientific research and how the role of institutional support and adequate funding can make research a success. Paabo's journey from Egyptian mummies to Mammoths, to Sloths and finally the Neanderthals and Denisovans is a great inspiration to all students of science. He shows how passion, perseverance, attention to detail, and collaboration can deliver results not only in Science but in all aspects of life.Paabo explains the Science very clearly and the narrative shows us how he has become the world's expert in 'ancient DNA'. But in order to do that he often has to go into intricate details of lab work which some readers might find difficult to follow. Still it will not affect the story and if you are interested to learn how we became what we are, this is a book that you should not miss.
The Neanderthal Man, by Svante, is a compelling recount by a principal in the discovery of genes of the Neanderthals. It starts with the interest in recovering DNA from old sources, and in this case some liver bought at the local market and then desiccated in an oven at 50C. The tale spans over some twenty years, with diversions typical of science, and ultimately ends with the publishing of some of the most interesting results in understanding man and his evolution.Svante is an exceptionally good writer and the tale flows quite smoothly. If one understands the science, then one can fill in the gaps and the tales is well presented. If one does not understand the science then one can still appreciate what is happening by taking the results presented at face value.The tale works back and forth from the fundamental science to the interrelationships between various players in the overall search. Svante shows how he managed to deal with the anthropologists and others to get samples of Neanderthals from as far away as Siberia. It also demonstrates some of the more cooperative nature of science as new techniques is shared and how Svante is assisted by many others who are but in related fields.The efforts span from California to Eastern Russia and it shows that in today's environment the ability to communicate changed what would have been multi-lifetime efforts into a fast paced move to provide the final answers.This book is a stark contrast to Watson's Double Helix. The Helix is a strong interplay of personalities; it portrays competitiveness and at times pettiness that is common in certain scientific endeavors. Helix was a true race, a sprint to get DNA right, and a succinct set of observations which became the underpinnings of Svante's efforts. Svante is the opposite of Watson. The ego is missing; the collegiality if present, yet one still sense the pace. Yet it is not a pace with an edge, it is a steady pace to get it right.This is definitely a great book for those seeking to understand the Neanderthal developments as well as understanding perhaps how the research community has matured as it has expanded.Also, upon some reflection, I recall when I first read Watson's Double Helix just after it was published I could recognize the highly competitive world of research since I was still at MIT. In contrast Svante portrays a totally different world, one more of communications and cooperation. The worlds of Watson and Svante are separated by some half century, and the difference is startling, one is near ruthless and the other collegial, with a sense of cooperation moving forward. Great job!
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